反応 #1797527

ord-2eea2dbb9b93479e963b376b993e4b27

反応方程式

O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
Intermediate 3
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl
5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide
NC1CCC1
cyclobutylamine
O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1NC1CCC1
5-Cyclobutylamino-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

5-Cyclobutylamino-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide was prepared using Procedure A from 5-chloro-1-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-ylamide (Intermediate 3) and cyclobutylamine. Mass spectrum (ES) MH+=391.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07790711B2uspto-grants-2010_09