反応 #1797471

反応方程式

2-(2-indenyl)indole

maleimide

→

white solid

収率 62.3%

4c,7a,7b,12a-Tetrahydro-6H,12H,13H-indeno[2,3-a]pyrrolo[3,4-c]carbazole-5,7-(5H, 7H)dione

収率 62.3%

溶媒

MeOH

反応条件

後処理

1. 1
   その他sealed
2. 2
   その他reaction
3. 3
   温度vial was heated at 180°-190° C. for 30 min
4. 4
   温度After cooling
5. 5
   その他the reaction to ambient temperature
6. 6
   その他The product was collected

実験手順

A mixture of 2-(2-indenyl)indole (1.0 g, 4.3 mmol) and maleimide (525 mg, 5.41 mmol) in a 10 cm sealed reaction vial was heated at 180°-190° C. for 30 min. After cooling the reaction to ambient temperature, MeOH (5 mL) was added. The product was collected to give 880 mg (62%) of a white solid product with a m.p. of 254°-255° C. (MeOH). The following NMR data were obtained: 1H NMR (DMSO-d6, 300 MHz): δ3.1-3.4 (m, 2H), 3.8 (m, 2H), 3.95 (t, 1H), 4.35 (d, 1H), 6.9-7.4 (m, 7H), 7.75 (d, 1H), 11.05 (s, 1H), 11.25 (s, 1H).

出典