反応 #1785943

ord-33e0914836b04e6d9c501d02386424b3

反応方程式

Cl.NC(CO)(CO)CO
Tris hydrochloric acid
COc1ccc(CC(C)=O)cc1OC
1-(3,4-dimethoxyphenyl)-2-propanone
C[C@@H](N)c1ccccc1
(R)-1-phenylethylamine
COc1ccc(C[C@@H](C)N)cc1OC
(R)-(3,4-dimethoxyphenyl)-2-aminopropane

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    抽出extract
  2. 2
    その他the components were reacted in 100 ml of a reaction mixture

実験手順

Using 10 ml of the cell-free extract, the components were reacted in 100 ml of a reaction mixture comprising a 0.1 M Tris-hydrochloric acid buffer (pH 8.5) containing 0.5 g of 1-(3,4-dimethoxyphenyl)-2-propanone and 0.34 g of (R)-1-phenylethylamine at 30° C. for 24 hours. As a result, 0.36 g of (R)-(3,4-dimethoxyphenyl)-2-aminopropane was formed.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06344351B2uspto-grants-2002_02