反応 #1771990

ord-56238b79bf8e4876a8c816dff94dc2f6

反応方程式

CC1(C)CN(C(=O)OC(C)(C)C)[C@@](C(=O)O)(C(C)(C)C)C1
tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline
CC1(C)CN[C@H](C(=O)O)C1
4,4-Dimethylproline

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    濃縮The solution was concentrated
  2. 2
    その他dried under high vacuum
  3. 3
    その他taken to the next step without further purification

実験手順

A solution of tert-butyl N-tert-butoxycarbonyl-4,4-dimethylproline in dichloromethane (5 mL) and trifluoroacetic (5 mL) was stirred at room temperature for five hours. The solution was concentrated, dried under high vacuum and taken to the next step without further purification.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: USRE043298E1uspto-grants-2012_04