反応 #1768456

ord-dc5e465f3d5545bab9192dbb8863fe65

反応方程式

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
→
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO.C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
Monoolein Taurocholic acid

反応物

C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO
monoolein
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.[Na+]
taurocholic acid

試薬

なし

溶媒

O
water

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他was stored at 10° C.

実験手順

860 mg of taurocholic acid was dissolved in 40 ml of de-ionized water. Then, 570.6 mg of monoolein was slowly added to the taurocholic acid solution using an ice bath on a sonic mixer. The final monolein and taurocholic acid concentration was 40 mM (the molecular weight of taurocholic acid is 537.7 and that of monoolein is 356.5). The mixture was stored at 10° C. until used.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05169944uspto-grants-1992_12