反応 #1755445

ord-0de7c4e7f1254c798623acd97ef71758

反応方程式

O=C(O)c1cc(=O)[nH][nH]1
3-carboxy-1H-pyrazol-5-one
CCOC(=O)CC(=O)C(=O)OCC
diethyl oxalacetate
NN
hydrazine
CCOC(=O)C1=CC(=O)N=N1
3-(carboethoxy)-pyrazol-5-one

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

3-carboxy-1H-pyrazol-5-one, for example, can thus be prepared by reacting diethyl oxalacetate with hydrazine to yield 3-(carboethoxy)-pyrazol-5-one, followed by refluxing in aqueous HCl solution to hydrolyze the ethyl ester.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07988740B2uspto-grants-2011_08