反応 #1747852

反応方程式

4-carboxyphenylthiourea

DIC

→

Phenylthiourea

溶媒

DMF

反応条件

後処理

1. 1
   その他Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651)
2. 2
   その他thus obtained
3. 3
   workup.ADDITIONThe glass surfaces thus treated
4. 4
   洗浄were then washed five times
5. 5
   その他for 3 minutes
6. 6
   その他at room temperature
7. 7
   洗浄After washing three times for three minutes each using respectively 30 mL of DCM at room temperature
8. 8
   その他the glass surfaces were dried
9. 9
   その他stored at 4° C. until further use

実験手順

4-carboxyphenylthiourea (Lancaster, 13047) was dissolved to 0.2M in DMF. The resultant mixture was activated by adding a half equivalent of DIC for 15 min at room temperature. Aminopropylsilylated glass surfaces purified with compressed air (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) were coated with the activated solution thus obtained and incubated for three hours at room temperature. The glass surfaces thus treated were then washed five times using respectively 30 mL of DMF for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

出典