反応 #1742176

反応方程式

3,3'-diaminodipropylamine

aldehydes

2-formylpyridine

imidazole-4-carboxaldehyde

→

base ( 36 )

1-(2-PYRIDYL)-11-(4-IMIDAZOLYL)-2,6,10-TRIAZAUNDECANE

溶媒

ethanol

反応条件

後処理

1. 1
   その他This compound was synthesized
2. 2
   その他After catalytic hydrogenation and purification by silica gel column chromatography

実験手順

This compound was synthesized as described in Example 4 by using 3,3'-diaminodipropylamine (4) (0.655 g, 0.005 mol) in dry ethanol and the two aldehydes pyridine-2-carboxaldehyde (2) (0.535 g, 0.005 mol) and imidazole-4-carboxaldehyde (34) (0.48 g, 0.005 mol) in that order. After catalytic hydrogenation and purification by silica gel column chromatography, the pure free base (36) was obtained (0.79 g). The product was transformed into the hydrochloride salt as described in Ex: 4

出典