反応 #1709248

ord-5003708023d74e28a7d6f43d24c0f7d0

反応方程式

CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O
stearidonic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
γ-linolenic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
dihomo-γ-linolenic acid
→
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
Linoleic acid
CCCCCCCC/C=C\CCCCCCCC(=O)O
oleic acid

反応物

CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O
stearidonic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
γ-linolenic acid
—
(n-3)-eicosatetraenoic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
dihomo-γ-linolenic acid

試薬

なし

溶媒

—
PUFA

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

A number of enzymes, most notably desaturases and elongases, are involved in PUFA biosynthesis (see FIG. 1). For example, an elongase (elo) catalyzes the conversion of γ-linolenic acid (GLA) to dihomo-γ-linolenic acid (DGLA) and of stearidonic acid (C18:4n-3) to (n-3)-eicosatetraenoic acid (C20:4n-3). Linoleic acid (LA, C18:2n-9,12 or C18:2n-6) is produced from oleic acid (C18:1-Δ9) by a Δ12-desaturase. GLA (C18:3n-6,9,12) is produced from linoleic acid by a Δ6-desaturase.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08778632B2uspto-grants-2014_07