反応 #1702337

反応方程式

(9-hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde

(S)-1-phenyl-propylamine

→

title compound

収率 50.0%

3,3-Dimethyl-9-{2-[(S)-1-phenyl-propylamino]-ethyl}-1,5-dioxa-spiro[5.5]undecan-9-ol

収率 50.0%

反応条件

実験手順

The title compound is prepared from (9-hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde and (S)-1-phenyl-propylamine following a procedure analogous to that described in Step 3 of Intermediate 2. Yield: 50% of theory; LC (method 8): tR=1.16 min; Mass spectrum (ESI+): m/z=362 [M+H]+.

出典