反応 #1702112

反応方程式

2-(3-nitrophenyl)ethanol

→

desired product

収率 99.0%

2-(3-Aminophenyl)ethanol

収率 99.0%

溶媒

methanol

反応条件

後処理

1. 1
   その他was hydrogenated at 45 psi overnight
2. 2
   ろ過The resultant mixture was filtered
3. 3
   濃縮concentrated

実験手順

Into a pressure bottle were added 2-(3-nitrophenyl)ethanol (3.0 g, 18 mmol) and methanol (100 mL) and 10% palladium on carbon (0.1 g, 0.08 mmol). The reaction mixture was hydrogenated at 45 psi overnight. The resultant mixture was filtered and concentrated to provide the desired product (2.44 g, 99%) as a white solid. LCMS for C8H12NO (M+H)+: m/z=138.1.

出典