反応 #1701281

反応方程式

2-bromochloroethane

1-methyl-5-(2-chloroethylthio)-1H-tetrazole

1,2-dibromoethane

3,5-diethoxycarbonyl-1H-pyrazole

→

1-methyl-5-(2-chloroethylthio)-1H-tetrazole

2-(1-methyl-5-(2-chloroethylthio)-1H-tetrazol-5-yl)ethyl chloride

反応条件

実験手順

When an equivalent amount of 1-methyl-5-(2-chloroethylthio)-1H-tetrazole is substituted for 3,5-diethoxycarbonyl-1H-pyrazole and an equivalent amount of 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 4, 2-(1-methyl-5-(2-chloroethylthio)-1H-tetrazol-5-yl)ethyl chloride is isolated after column chromatography 1-methyl-5-(2-chloroethylthio)-1H-tetrazole, Aldrich, 59%, A).

出典