反応 #1695358

反応方程式

2-quinolinecarboxaldehyde

m-toluic acid hydrazide

→

title compound

収率 36.2%

3-methylbenzoic acid (2-quinolinylmethyl-ene)hydrazide

収率 36.2%

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The hot solution is filtered
2. 2
   workup.ADDITIONthen diluted with water until cloudy
3. 3
   温度chilled
4. 4
   その他The solid is collected

実験手順

A mixture of 3.3 gm (0.021 mole) of 2-quinolinecarboxaldehyde, 3.15 gm (0.021 mole) of m-toluic acid hydrazide and 150 ml of absolute ethanol is refluzed 10 hr. The hot solution is filtered then diluted with water until cloudy. The mixture is cooled to room temperature and then chilled. The solid is collected to give 2.2 gm (36%) of the title compound having a melting point of 187.5°-188° C. after recrystallizing from methylene chloride/diethyl ether.

出典