反応 #1694092

ord-8b213370aef341cd831978c58575539f

反応方程式

COC(=O)c1cc(Cl)c(NC(C)=O)c2c1OC1CCCCC21
methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylate
COC(=O)c1cc(Cl)c(NC(C)=O)c2c3c(oc12)CCCC3
methyl 1-acetylamino-2-chloro-6,7,8,9-tetrahydro-dibenzofuran-4-carboxylate
COC(=O)c1cc(Cl)c(NC(C)=O)c2c1oc1ccccc12
methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate
→
Nc1c(Cl)cc(C(=O)O)c2oc3c(c12)CCCC3.Nc1c(Cl)cc(C(=O)O)c2oc3ccccc3c12
1-AMINO-2-CHLORO-6,7,8,9-TETRAHYDRODIBENZOFURAN-4-CARBOXYLIC ACID 1-AMINO-2-CHLORODIBENZOFURAN-4-CARBOXYLIC ACID

反応物

COC(=O)c1cc(Cl)c(NC(C)=O)c2c1OC1CCCCC21
methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylate
COC(=O)c1cc(Cl)c(NC(C)=O)c2c3c(oc12)CCCC3
methyl 1-acetylamino-2-chloro-6,7,8,9-tetrahydro-dibenzofuran-4-carboxylate
COC(=O)c1cc(Cl)c(NC(C)=O)c2c1oc1ccccc12
methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他the captioned products are prepared

実験手順

When the procedure of Example 15 is followed however methyl 1-acetylamino-2-chloro-5a,6,7,8,9,9a-hexahydrodibenzofuran-4-carboxylate is replaced by methyl 1-acetylamino-2-chloro-6,7,8,9-tetrahydro-dibenzofuran-4-carboxylate or methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate then the captioned products are prepared.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04863921uspto-grants-1989_09