反応 #1691232

反応方程式

phthalic anhydride

2,2,4-trimethyl-1,3-pentanediol

→

7-Isopropyl-8,8-dimethyl-8,9-dihydro-7H-6,10-dioxabenzocyclononene-5,11-dione

収率 40.0%

溶媒

xylene

反応条件

後処理

1. 1
   その他Xylene was removed on a rotary evaporator
2. 2
   workup.DISTILLATIONthe residue distilled
3. 3
   その他to give 11.09 g of distillate, b0.5 130-160° C. which

実験手順

Following the procedure of Examples 1 or 2,7-Isopropyl-8,8-dimethyl-8,9-dihydro-7H-6,10-dioxabenzocyclononene-5,11-dione was prepared from a solution of 14.81 g (0.1 mole) of phthalic anhydride and 16.30 g (0.11 mole) of 2,2,4-trimethyl-1,3-pentanediol (TMPD) in 75 mL of xylene. The catalyst was 49.4 mg of FASCAT® 4100 catalyst. Xylene was removed on a rotary evaporator and the residue distilled to give 11.09 g of distillate, b0.5 130-160° C. which was found by vapor phase chromatography (vpc) to consist of 84% of 7-Isopropyl-8,8-dimethyl-8,9-dihydro-7H-6,10-dioxabenzocyclononene-5,11-dione (40% yield). The residue from this distillation weighed 17.65 g.

出典