反応 #168903

反応方程式

4-(4-aminophenylthio)-N-(4-morpholinophenyl)pyrimidin-2-amine

cyanoacetic acid

→

product

収率 68.0%

N-(4-(2-(4-morpholinophenylamino)pyrimidin-4-ylthio)phenyl)-2-cyanoacetamide

収率 68.0%

反応条件

実験手順

In a procedure analogous to Example 15, reaction of 4-(4-aminophenylthio)-N-(4-morpholinophenyl)pyrimidin-2-amine (60 mg, 0.16 mmol) and cyanoacetic acid (46 mg, 0.32 mmol) furnished the product (48 mg, 68%).

出典