反応 #1687626

反応方程式

3-pyridyl acetylene

trimethylsilyl azide

→

4-(3-Pyridyl)-1,2,3-triazole

溶媒

water

反応条件

後処理

1. 1
   温度After cooling the mixture
2. 2
   その他A colorless solid, 68, formed
3. 3
   その他which was isolated by filtration
4. 4
   その他dried

実験手順

In a glass-coated bomb tube 6.5 g (0.063 mol) of 3-pyridyl acetylene (T. Sakamoto et al., Synthesis (1983) 312) and 8.7 g (0.075 mol) of trimethylsilyl azide were mixed and heated to 150° C. for 20 h. After cooling the mixture was poured into water. A colorless solid, 68, formed, which was isolated by filtration and dried. Yield: 4.0 g (0.028 mol, 44%).

出典