反応 #1687619

反応方程式

3-Cyanopyridine

methyl iodide

methyl iodide

→

title compound

収率 81.0%

3-Cyano-1-methylpyridinium Iodide

収率 81.0%

溶媒

acetone

反応条件

後処理

1. 1
   ろ過The mixture was filtered
2. 2
   洗浄the solid product was washed with acetone (100 ml)
3. 3
   その他After drying

実験手順

3-Cyanopyridine (1) (104 g, 1 mol) and methyl iodide (150 g, 1.06 mol) in acetone (500 ml) was stirred for 5 hours at room temperature. Then more methyl iodide (20 g, 0.14 mol) was added, and the reaction mixture was stirred overnight at room temperature. The mixture was filtered and the solid product was washed with acetone (100 ml) and then thoroughly with ether. After drying, 199 g (0.81 mol, 81%) of the title compound were obtained, M.P. 145°-150° C.

出典