反応 #167752

反応方程式

2-Bromo-9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepine

4-(2-(1H-imidazol-1-yl)ethoxy)phenyl boronic acid

→

9-(2-chloro-3,6-difluorobenzyl)-2-{4-[2-(1H-imidazol-1-yl)ethoxy]phenyl}-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepine

反応条件

実験手順

The entitled compound can be prepared from 2-Bromo-9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepine and 4-(2-(1H-imidazol-1-yl)ethoxy)phenyl boronic acid as described in example 1 or 30.

出典