反応 #1676

反応方程式

6-(4-chlorophenyl)-pyridazinone

phosphorus pentasulfide

→

6-(4-chlorophenyl)-pyridazinthione

収率 187.1%

溶媒

pyridine

反応条件

後処理

1. 1
   温度was refluxed for 1 hour
2. 2
   その他evaporated to dryness
3. 3
   抽出extracted with 200 ml of ether
4. 4
   抽出The ether extract
5. 5
   洗浄was washed with water (3×100 ml), brine (100 ml)
6. 6
   乾燥dried over magnesium sulfate
7. 7
   その他evaporated

実験手順

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

出典