反応 #167201

反応方程式

2,3-dimethylaniline

chloroacetyl chloride

n-butyl-isothiocyanate

→

2-[(Z)-n-butylimino]-3-(2,3-dimethylphenyl)-thiazolidin-4-one

反応条件

実験手順

2-[(Z)-n-butylimino]-3-(2,3-dimethylphenyl)-thiazolidin-4-one is prepared following Method B and starting from 2,3-dimethylaniline, chloroacetyl chloride and n-butyl-isothiocyanate. LC-MS: tR=0.80 min, [M+1]+=277, 1H NMR (CDCl3): δ 7.23-7.16 (m, 2H), 6.99-6.94 (m, 1H), 4.01 (s, 2H), 3.38-3.23 (m, 2H), 2.33 (s, 3H), 2.05 (s, 3H), 1.59-1.49 (m, 2H), 1.38-1.25 (m, 2H), 0.91 (t, J=7.0 Hz, 3H).

出典