反応 #167198

反応方程式

o-tolylamine

chloroacetyl chloride

ethylisothiocyanate

→

2-[(Z)-Ethylimino]-3-(2-methylphenyl)-thiazolidin-4-one

反応条件

実験手順

2-[(Z)-Ethylimino]-3-(2-methylphenyl)-thiazolidin-4-one is prepared following Method B and starting from o-tolylamine, chloroacetyl chloride and ethylisothiocyanate. LC-MS: tR=0.59 min, [M+1]+=235, 1H NMR (CDCl3): δ 7.36-7.28 (m, 3H), 7.15-7.10 (m, 1H), 4.01 (s, 2H), 3.41-3.30 (m, 2H), 2.19 (s, 3H), 1.20-1.13 (m, 3H).

出典