反応 #166003

ord-720e84359df4462da2333b9203e63c1f

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他LC/MS [9.86 min; 412 (M+1)]

実験手順

N-(cyclobutyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.34 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.42 mmol of cyclobutylamine. LC/MS [9.86 min; 412 (M+1)]

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08841459B2uspto-grants-2014_09