反応 #165546

反応方程式

5-amino-2-methylphenol

4-chloro-N-methyl-2-pyridinecarboxamide

→

3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline

反応条件

後処理

1. 1
   その他had been synthesized

実験手順

Entry 50: According to Method A2, Step 4, 5-amino-2-methylphenol was reacted with 4-chloro-N-methyl-2-pyridinecarboxamide, which had been synthesized according to Method A2, Step 3b, to give 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline. According to Method C1a, 4-chloro-3-(trifluoromethyl)phenyl isocyanate was reacted with 3-(2-(N-methylcarbamoyl)-4-pyridyloxy)-4-methylaniline to afford the urea.

出典