反応 #164024

反応方程式

L-tert-leucine

diisopropyl ether

→

D-tert-leucine

収率 90.0%

溶媒

acetone

反応条件

後処理

1. 1
   その他to remove any traces of dibenzoyl-d-tartaric acid
2. 2
   濃縮was concentrated under reduced pressure at 55° C
3. 3
   その他The residue obtained
4. 4
   ろ過filtered

実験手順

The filtrate obtained at dibenzoyl-d-tartrate salt stage (step.ii), was treated with a small amount of diisopropyl ether to remove any traces of dibenzoyl-d-tartaric acid and was concentrated under reduced pressure at 55° C. The residue obtained was stirred with small amount of acetone and filtered to obtain D-tert-leucine as a colorless solid (90% yield, 98.8% D-tert-leucine and 1.2% L-tert-leucine).

出典