反応 #163525

反応方程式

THF

pentafluorobenzoyl chloride

NaH

oxazinone

→

2-ethyl-4-(perfluorophenylcarbonyl)-8-(prop-1-enyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

収率 63.0%

反応条件

後処理

1. 1
   その他240 mg of P5 were obtained

実験手順

Procedure & NMR Data: 265 μL of pentafluorobenzoyl chloride (2 eq, 1.84 mmol) was added to a mixture of 148 mg of NaH (4 eq, 3.68 mmol) and 200 mg (0.92 mmol) of oxazinone P2 in THF (22 ml). 240 mg of P5 were obtained, yield 63%.

出典