反応 #1628

反応方程式

3-benzyloxypropyl-(4-chlorobenzenesulfonyloxymethyl)phosphinic acid, n-butyl ester

2-(4-hydroxyphenyl)ethylcarbamic acid, t-butyl ester

→

title compound

4-(2-t-Butoxycarbonylaminoethyl)phenoxymethyl-(3-benzyloxypropyl)phosphinic acid, n-butyl ester

反応条件

後処理

1. 1
   その他The crude product was purified by chromatography
2. 2
   洗浄eluting with dichloromethane containing 3% methanol
3. 3
   その他to give an oil

実験手順

The title compound was prepared from 3-benzyloxypropyl-(4-chlorobenzenesulfonyloxymethyl)phosphinic acid, n-butyl ester and 2-(4-hydroxyphenyl)ethylcarbamic acid, t-butyl ester according to the procedure described in Procedure 24. The crude product was purified by chromatography, eluting with dichloromethane containing 3% methanol, to give an oil.

出典