反応 #161303

反応方程式

n-Butyraldehyde

1,2-propanediol

→

n-Butyraldehyde 1,2-Propanediol

反応条件

後処理

1. 1
   その他The system is purged with nitrogen three times
2. 2
   workup.ADDITIONThen 500 psi of hydrogen is charged
3. 3
   workup.ADDITIONconversion of n-butyraldehyde and formation of an approximately 1:1 mixture of 2-butoxy-1-propanol and 1-butoxy-2-propanol (79.2%), n-butanol (5.8%), and cis/trans 2-propyl-4-methyl-1,3-dioxolane (11.9%)

実験手順

n-Butyraldehyde (3.6 g, 4.5 ml; 0.05 mol), 1,2-propanediol (76.1 g, 73.4 ml; 1 mol), and 0.18 g of 10% Pd/C (5 wt % to n-butyraldehyde) are charged to a 150 ml Parr reactor. The system is purged with nitrogen three times. Then 500 psi of hydrogen is charged, the reactor is heated to 180° C., and the hydrogen pressure is adjusted to 1000 psi. After 3 hours at 180° C. and 1000 psi, GC analysis shows complete conversion of n-butyraldehyde and formation of an approximately 1:1 mixture of 2-butoxy-1-propanol and 1-butoxy-2-propanol (79.2%), n-butanol (5.8%), and cis/trans 2-propyl-4-methyl-1,3-dioxolane (11.9%).

出典