反応 #1610

反応方程式

2-bromo-p-chloroacetophenone

methoxythiocarbonylhydrazine

→

5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one

収率 48.4%

溶媒

acetonitrile

反応条件

後処理

1. 1
   温度was refluxed overnight
2. 2
   温度cooled
3. 3
   ろ過filtered
4. 4
   洗浄The light yellow solid was washed with hexane
5. 5
   その他dried

実験手順

A mixture of 2-bromo-p-chloroacetophenone (9.16 g), methoxythiocarbonylhydrazine (13.0 g) and acetonitrile (75 ml) was refluxed overnight and then cooled and filtered. The light yellow solid was washed with hexane and dried yielding 5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one (4.3 g).

出典