反応 #160983

反応方程式

5-bromo-6-chloronicotinic acid

4-(2-chloro-1,1,2,2-tetrafluoroethyl)aniline

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title compound

5-Bromo-6-chloro-N-(4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl)nicotinamide

反応条件

後処理

1. 1
   その他to afford a beige crystalline powder

実験手順

The title compound was prepared in an analogous fashion to that described in Stage 9.3 using 5-bromo-6-chloronicotinic acid and 4-(2-chloro-1,1,2,2-tetrafluoroethyl)aniline (Stage 31.3) to afford a beige crystalline powder. HPLC (Condition 4) tR=6.77 min, UPLC-MS (Condition 3) tR=1.31 min, m/z=444.8 [M+H]+.

出典