反応 #160656

反応方程式

bufexamac

2a

Bufexamac

1-methoxy-2-propanol

urethane

bufexamac

2a

Bufexamac

2b

Methacrylate

→

Methylstyrene

反応条件

後処理

1. 1
   その他respectively, were prepared
2. 2
   その他The solution was then dried down to a powder, under vacuum, at 70° C
3. 3
   その他A total of 4.93 grams of zirconia nanoparticle powder was recovered
4. 4
   workup.ADDITIONredispersed in 4.93 grams of ultra-pure THF
5. 5
   その他to yield a clear, slightly yellow solution
6. 6
   workup.ADDITIONTo this solution 0.48 grams of 3-isopropenyl-α,α-dimethylbenzyl isocyanine was added
7. 7
   その他The vial was sealed
8. 8
   workup.STIRRINGstirred for 12 hours at room temperature

実験手順

Functionalized zirconia nanoparticles in which 50%, 25%, and 25% of the surface sites reacted with bufexamac, 2a (Preparatory Example 1), and 2b (Preparatory Example 2), respectively, were prepared as follows. A clean vial was charged with 10 grams of ZrO2 sol (47.3% weight) followed by 20 grams of 1-methoxy-2-propanol. Then 0.739 grams (0.70 mmol/g ZrO2) of bufexamac, 0.383 grams (0.35 mmol/g ZrO2) of 2a and 0.243 grams (0.35 mmol/g ZrO2) 2b were added to the vial. The content of the vial was stirred for 2 hours. The solution was then dried down to a powder, under vacuum, at 70° C. A total of 4.93 grams of zirconia nanoparticle powder was recovered. The powder was placed in a clean vial and redispersed in 4.93 grams of ultra-pure THF to yield a clear, slightly yellow solution. To this solution 0.48 grams of 3-isopropenyl-α,α-dimethylbenzyl isocyanine was added. The vial was sealed and stirred for 12 hours at room temperature. An FT-IR was taken of the sample, and an IR peak was observed at 1751 cm−1 and attributed to the ν(C═O) stretch in the urethane.

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