反応 #1605811

反応方程式

2-Phenylaniline

acetic anhydride

→

2-phenyl-N-acetylaniline

収率 99.5%

溶媒

acetic acid

反応条件

後処理

1. 1
   濃縮The solution was concentrated under reduced pressure
2. 2
   workup.ADDITIONto the residue was added water (15 mL)
3. 3
   workup.STIRRINGthe mixture was stirred at room temperature for 3 hours
4. 4
   ろ過The precipitate was collected by filtration
5. 5
   洗浄washed with purified water
6. 6
   その他dried under reduced pressure

実験手順

2-Phenylaniline (5 g, 29.55 mmol) was dissolved in acetic acid (30 mL), acetic anhydride (3.62 g, 35.45 mmol) was added thereto under ice bath, and the mixture was stirred under ice bath for 2 hours. The solution was concentrated under reduced pressure. to the residue was added water (15 mL), and the mixture was stirred at room temperature for 3 hours. The precipitate was collected by filtration, washed with purified water, and dried under reduced pressure to obtain 2-phenyl-N-acetylaniline (6.21 g).

出典