反応 #1605802
ord-61c1f225522147deb20973421acd404a
反応方程式
tert-butyl 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate
hydrochloric acid
→
3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate hydrochloride
反応物
試薬
なし
溶媒
反応条件
温度
70°CELSIUS
詳細条件
See reaction.notes.procedure_details.
後処理
- 1濃縮The reaction solution was concentrated under reduced pressure
実験手順
To tert-butyl 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate (5.08 g, 11.6 mmol) was added a 4M solution of hydrochloric acid in dioxane (70 mL) and the mixture was stirred at 70° C. for 2 hours. The reaction solution was concentrated under reduced pressure to obtain 3-[3-({[(1-methylpiperidin-4-yl)oxy]carbonyl}amino)-4-phenylphenyl]propionate hydrochloride (5.49 g).