反応 #1596997

反応方程式

5-aminosalicylic acid

4-(trifluoromethyl)benzyl chloride

→

5-(4-(trifluoromethyl)benzyl)aminosalicylic acid

収率 50.3%

反応条件

後処理

1. 1
   その他in Synthesis Example 1

実験手順

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-(trifluoromethyl)benzyl chloride (760 mg, 3.92 mmole), 510 mg (50% yield) of 5-(4-(trifluoromethyl)benzyl)aminosalicylic acid was obtained as a white solid.:mp>188° C. (decompose).

出典