反応 #1596980

反応方程式

water

2-phenylethylamine

2-fluoronitrobenzene

potassium carbonate

→

orange crystals

収率 98.0%

N-Phenylethyl-2-nitroaniline

収率 98.0%

溶媒

DMSO

反応条件

後処理

1. 1
   温度The mixture was then cooled to ambient temperature
2. 2
   その他resulted in the precipitation of a light orange compound
3. 3
   ろ過The solid was recovered by filtration
4. 4
   その他dried

実験手順

A mass of 4.8 g (0.04 mol) of 2-phenylethylamine was added dropwise, at ambient temperature, to a mixture of 5.6 g (0.04 mol) of 2-fluoronitrobenzene and 11.06 g (0.08 mol) of anhydrous potassium carbonate in 30 ml of DMSO. The mixture was heated at 100° C. for 3 hours. The mixture was then cooled to ambient temperature and was added to 100 ml of water, which resulted in the precipitation of a light orange compound. The solid was recovered by filtration and dried using a desiccator at reduced pressure. A mass of 9.4 g of orange crystals was obtained with a yield of 98%. The melting point found was coherent with the theoretical value, i.e. 64-66° C.

出典