反応 #1596523

反応方程式

diphenyliodonium chloride

triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate

water

→

target compound

収率 96.6%

Diphenyliodonium 2-Pivaloyloxy-1,1-difluoroethanesulfonate

収率 96.6%

溶媒

chloroform

反応条件

後処理

1. 1
   その他reacted at room temperature for 3 hours
2. 2
   その他The thus-obtained reaction solution
3. 3
   その他was separated into an organic layer
4. 4
   洗浄The organic layer was washed five times with 15 mL of water
5. 5
   濃縮subjected to concentration under reduced pressure

実験手順

In 10 mL of chloroform, 5 g of a solid of triethylammonium 2-pivaloyloxy-1,1-difluoroethanesulfonate (equivalent to 14.4 mmol) was dissolved by stirring. The resulting solution was admixed with 15 mL of water and 4.78 g (15.1 mmol) of diphenyliodonium chloride, and then, reacted at room temperature for 3 hours. The thus-obtained reaction solution was separated into an organic layer and an aqueous layer. The organic layer was washed five times with 15 mL of water and subjected to concentration under reduced pressure. With this, 7.32 g of the target compound was obtained as a white solid (purity: 90%, yield: 90%).

出典