反応 #159617

反応方程式

azetidin-3-ol hydrochloride

methyl 2-chloro-5-fluoronicotinate

→

title compound ( D70 )

methyl 5-fluoro-2-(3-hydroxyazetidin-1-yl)nicotinate

反応条件

実験手順

The title compound (D70) (75 mg) was prepared according to the experimental procedure described in Description 62 starting from azetidin-3-ol hydrochloride (208 mg, 1.89 mmol) and methyl 2-chloro-5-fluoronicotinate (300 mg, 1.58 mmol, commercially available from Adesis#2-482).

出典