反応 #158560

反応方程式

N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine

2,4-dichloro-5-methylpyrimidine

3-hydroxyaniline

→

N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine

反応条件

実験手順

In a manner analogous to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,4-dichloro-5-methylpyrimidine with 3-hydroxyaniline gave N2,N4-bis(3-hydroxyphenyl)-5-methyl-2,4-pyrimidinediamine. LCMS: ret. time: 16.76 min.; purity: 100%, MS (m/e): 309 (MH+).

出典