反応 #158379

反応方程式

methyl 4-(4-chloro-1H-imidazol-1-yl)-3-methoxybenzoate

hydrazine monohydrate

→

title compound

4-(4-chloro-1H-imidazol-1-yl)-3-methoxybenzohydrazide

溶媒

methanol

反応条件

後処理

1. 1
   その他the solvent was evaporated under reduced pressure
2. 2
   洗浄The residue was washed with ethyl acetate

実験手順

To a mixture of methyl 4-(4-chloro-1H-imidazol-1-yl)-3-methoxybenzoate (25.5 mg) in methanol (1 mL) was added hydrazine monohydrate (0.019 mL) at room temperature, the mixture was stirred at 60° C. overnight, and the solvent was evaporated under reduced pressure. The residue was washed with ethyl acetate to give the title compound (12.7 mg).

出典