反応 #158241

ord-75a4634ab12f4e5e94128d63d8b7edb5

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In some embodiments, after reacting 1-(4-chlorophenethylamino)propan-2-ol with thionyl chloride, produces 2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride with a purity of about 95% or greater as determined by HPLC. In some embodiments, after reacting 1-(4-chlorophenethylamino)propan-2-ol with thionyl chloride, the 2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride with a purity of about 98% or greater as determined by HPLC. In some embodiments, “HPLC” refers to Reversed-Phase High Performance Liquid Chromatography. In some embodiments, “HPLC” refers to Normal-Phase High Performance Liquid Chromatography.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08822727B2uspto-grants-2014_09