反応 #156597

反応方程式

Trifluoromethanesulfonic acid 2-[4-((R)-3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl ester

4-methoxypiperidine

→

2-[4-((R)-3-Dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-6-(4-methoxypiperidin-1-yl)-3,4-dihydro-2H-isoquinolin-1-one

反応条件

後処理

1. 1
   その他The product with the molecular weight of 466.60 (C27H35FN4O2) was obtained in this way

実験手順

Trifluoromethanesulfonic acid 2-[4-((R)-3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl ester was reacted with 4-methoxypiperidine by method N. The product with the molecular weight of 466.60 (C27H35FN4O2) was obtained in this way; MS (ESI): 467 (M+H+).

出典