反応 #156592

ord-d2c5c17b53004ccd883e72f32cd67d1d

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他The product with the molecular weight of 517.67 (C27H36FN3O4S) was obtained in this way

実験手順

6-Butoxy-2-[3-fluoro-4-((R)-3-methylaminopyrrolidin-1-yl)phenyl]-3,4-dihydro-2H-isoquinolin-1-one was reacted with methanesulfonylethene by method G. The product with the molecular weight of 517.67 (C27H36FN3O4S) was obtained in this way; MS (ESI): 518 (M+H+).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08822495B2uspto-grants-2014_09