反応 #1562

反応方程式

1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione

hydrogen

→

title product

1-(5-Amino-2-chloro-4-fluorophenyl)-3-methyl-s-triazine

溶媒

ethyl acetate

反応条件

後処理

1. 1
   ろ過The reaction mixture is then filtered
2. 2
   濃縮concentrated in vacuo

実験手順

A mixture of 1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione (28.5 g, 0.09 mol) and 5% platinum on activated carbon (1 g) in ethyl acetate is hydrogenated at 55 psi until hydrogen uptake is complete. The reaction mixture is then filtered and concentrated in vacuo to give the title product as a white solid, mp 244°-245° C.

出典