反応 #155407
ord-93a3b2b663214d489cd4f62b05f10f19
反応方程式
N-Boc-3-azetidinone
ethanolamine
→
N—(N-Boc-azetidin-3-yl)-2-amino-ethanol
収率 62.3%
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
N-Boc-3-azetidinone (1.0 g, 5.84 mmol) was treated with ethanolamine following Procedure 1-Method A to yield N—(N-Boc-azetidin-3-yl)-2-amino-ethanol (0.75 g, 3.46 mmol, 62.3% yield): MS m/e [M+H]+ calcd 217.1. found 217.2.