反応 #155392

反応方程式

4-(tert-butyldimethylsilyloxy)phenyl acridin-9-carboxylate

methyl trifluoromethanesulfonate

→

4-(tert-butyldimethylsilyloxy)phenyl 10-methylacridinium-9-carboxylate trifluoromethanesulfonate

溶媒

dichloromethane

反応条件

後処理

1. 1
   その他Into a 50 mL round bottom flask equipped with magnetic stirrer under argon atmosphere
2. 2
   ろ過Bright yellow solid was collected by filtration
3. 3
   洗浄washed with 2×1 mL of dichloromethane and air
4. 4
   その他dried for 4 hr

実験手順

Into a 50 mL round bottom flask equipped with magnetic stirrer under argon atmosphere charged a solution of 1.6 parts of 4-(tert-butyldimethylsilyloxy)phenyl acridin-9-carboxylate in 25 mL of dichloromethane. 3.2 Parts of methyl trifluoromethanesulfonate was added to the solution and stirred for 40 hrs at room temperature. Bright yellow solid was collected by filtration, washed with 2×1 mL of dichloromethane and air dried for 4 hr to yield 1.44 parts of 4-(tert-butyldimethylsilyloxy)phenyl 10-methylacridinium-9-carboxylate trifluoromethanesulfonate having the following structure confirmed by NMR.

出典