反応 #1552095

反応方程式

3-(3,3-dimethylbut-1-yn-1-yl)aniline

hydrogen

→

3-(3,3-dimethylbutyl)cyclohexanamine

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   ろ過the catalyst is filtered off through kieselguhr
2. 2
   濃縮the product is concentrated under reduced pressure

実験手順

0.5 g of Ru/C 5% is added to a solution consisting of 1.04 g (0.6 mol) of 3-(3,3-dimethylbut-1-yn-1-yl)aniline in 20 ml of tetrahydrofuran, and the mixture is hydrogenated with 100 bar of hydrogen at 120° C. for 40 hours. After cooling to room temperature, the catalyst is filtered off through kieselguhr and the product is concentrated under reduced pressure. This gives 0.9 g (81% of theory) of 3-(3,3-dimethylbutyl)cyclohexanamine as main component according to MSD-HPLC.

出典