反応 #1552054

反応方程式

methyl-4-bromobenzoate

hydrazine monohydrate

→

white solid

収率 67.0%

4-bromobenzohydrazide

収率 67.0%

溶媒

ethanol

反応条件

後処理

1. 1
   温度the mixture was heated
2. 2
   workup.STIRRINGstirred at 78° C. for 5 hours
3. 3
   その他A solid obtained
4. 4
   洗浄washed with water
5. 5
   ろ過collected by suction filtration

実験手順

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added therein, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added therein, and the mixture was heated and stirred at 78° C. for 5 hours. A solid obtained washed with water and collected by suction filtration; thus, 2.0 g of a white solid of objective 4-bromobenzohydrazide was obtained (yield: 67%).

出典