反応 #1552050

反応方程式

1,8-octanediamine

triethylamine

furoyl chloride

→

N,N′-(octane-1,8-diyl)bis(furan-2-carboxamide)

反応条件

後処理

1. 1
   その他The resulting compound was purified by column chromatography (98:2 DCM:EtOAc)
2. 2
   その他the product obtained as a white solid (21.5 g/92%)

実験手順

The general procedure was carried out using 1,8-octanediamine (10.0 g, 69.3 mmol), triethylamine (14.2 g, 141 mmol), DMAP (0.17 g, 1.35 mmol) and furoyl chloride (19.0 g, 146 mmol). The resulting compound was purified by column chromatography (98:2 DCM:EtOAc), and the product obtained as a white solid (21.5 g/92%).

出典