反応 #1547446

反応方程式

4-methoxybenzyl chloride

2-chloropyridine

sodium hexafluoroantimonate

→

title compound

4-methoxybenzyl-2-chloropyridinium hexafluoroantimonate

溶媒

methanol

反応条件

後処理

1. 1
   その他After the reaction
2. 2
   その他the solvent was evaporate in vacuo and ether-water
3. 3
   workup.ADDITIONwas added to the residue
4. 4
   抽出to extract unreacted reactants in the etherial layer
5. 5
   workup.ADDITIONTo the aqueous layer containing the pyridinium chloride
6. 6
   ろ過filtered
7. 7
   洗浄washed
8. 8
   その他dried

実験手順

4,698 g (0.03 mol) of 4-methoxybenzyl chloride and 10.22 g (0.09 mol) of 2-chloropyridine were reacted in 40 ml of methanol at 40° C. for 3 days. After the reaction, the solvent was evaporate in vacuo and ether-water was added to the residue to extract unreacted reactants in the etherial layer. To the aqueous layer containing the pyridinium chloride was added 7.764 g (0.03 mol) of sodium hexafluoroantimonate. The resulting crystals were suction filtered, washed and dried to give the title compound melting at 122°-124° C.

出典