反応 #1543034

反応方程式

N-(2-mercaptoethyl)glutaramic acid

ammonia

→

N-(2-Mercaptoethyl)glutaramide

反応条件

後処理

1. 1
   その他After evaporation
2. 2
   その他to dryness and recrystallization from isopropanol 7 g of N-(2-mercaptoethyl)glutaramide
3. 3
   その他were obtained in the form of a white solid with a melting point of 127° C.

実験手順

A solution of 9.1 g (44 mmol) of methyl ester of N-(2-mercaptoethyl)glutaramic acid obtained in Example 4a), in 100 cm3 of aqueous 20% solution of aqueous ammonia was stirred for 4 hours at ambient temperature under argon atmosphere. After evaporation to dryness and recrystallization from isopropanol 7 g of N-(2-mercaptoethyl)glutaramide were obtained in the form of a white solid with a melting point of 127° C.

出典